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17-Phenyl Trinor Prostaglandin F2Alpha CAS NO 38344-08-0


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CAS No.:38344-08-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

17-Phenyl Trinor Prostaglandin F2Alpha is a synthetic prostaglandin analog, a key intermediate in the research and development of advanced pharmaceutical compounds. This high-purity intermediate is critical for ensuring the efficacy and consistency of final active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on ophthalmology, reproductive health, and other therapeutic areas involving prostaglandin pathways.

Application

  • Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of prostaglandin-based ophthalmic drugs for glaucoma treatment.
  • Biochemical Research: Used as a reference standard and probe in pharmacological studies to investigate prostaglandin receptor activity and signaling pathways.
  • Fine Chemical Synthesis: Employed in the multi-step synthesis of more complex prostaglandin analogs and derivatives for therapeutic applications.
  • Academic & Contract Research: Essential for universities and CROs (Contract Research Organizations) conducting pre-clinical research in reproductive medicine and inflammation.
  • Process Development: Used in scaling up and optimizing synthetic routes for prostaglandin APIs under cGMP conditions.
  • Analytical Standard: Functions as a high-purity standard for HPLC, LC-MS, and other analytical methods to ensure quality control in API manufacturing.

Basic Information

Product Name 17-Phenyl Trinor Prostaglandin F2Alpha
CAS No. 38344-08-0
Molecular Formula C₂₃H₃₂O₅
Molecular Weight 388.50 g/mol
Synonyms 17-Phenyl-13,14-dihydrotrinor Prostaglandin F2α; 17-Phenyl-18,19,20-trinor Prostaglandin F2α; PGF2α 17-phenyl trinor analog; Travoprost Impurity; Travoprost Related Compound; 9α,11α,15S-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5Z,13E-dien-1-oic acid; AL-6221
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Quality Control

Our 17-Phenyl Trinor Prostaglandin F2Alpha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with the standards required for pharmaceutical intermediates in research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is hygroscopic (moisture-sensitive) and must be handled in a dry environment to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0%
Water Content (KF) ≤ 0.5%
Residual Solvents (GC) Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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