Description

(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(S)-3-Hydroxy-5-Phenyl-Pent-1-Enyl)-Cyclopentyl]-Hept-5-Enoic Acid Methyl Ester is a high-purity, stereochemically defined prostaglandin intermediate of significant synthetic interest. This compound is valued for its role as a key chiral building block in the synthesis of complex bioactive molecules, particularly prostaglandin analogs. It is essential for research and development in the pharmaceutical and fine chemical sectors, where precise stereochemistry and high purity are critical for successful outcomes.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the multi-step synthesis of prostaglandin-based active pharmaceutical ingredients (APIs).
• Prostaglandin Analog Synthesis: Used in the research and production of prostaglandin E and F series analogs for potential therapeutic applications.
• Medicinal Chemistry Research: Serves as a valuable tool for structure-activity relationship (SAR) studies and the development of new drug candidates targeting inflammation, cardiovascular function, and ocular pressure.
• Fine Chemical Synthesis: Employed in advanced organic synthesis for constructing complex, polyfunctional molecules with multiple stereocenters.
• Biochemical Research: Used as a standard or reference compound in studies investigating prostaglandin pathways and receptor interactions.

Basic Information

Product Name	(Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(S)-3-Hydroxy-5-Phenyl-Pent-1-Enyl)-Cyclopentyl]-Hept-5-Enoic Acid Methyl Ester
CAS No.	38315-47-8
Molecular Formula	C25H36O6
Molecular Weight	432.55 g/mol
Synonyms	Methyl (5Z,13E)-(9R,11R,15S)-9,11,15-Trihydroxy-17-phenyl-18,19,20-trinorprosta-5,13-dien-1-oate; PGF2α Methyl Ester Intermediate; 17-Phenyl-18,19,20-trinor-PGF2α Methyl Ester; (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3S)-3-hydroxy-5-phenyl-1-penten-1-yl]cyclopentyl]-5-heptenoic Acid Methyl Ester; Prostaglandin F2α Analogue Methyl Ester; 38315-47-8; Methyl ester of (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-((E)-(S)-3-hydroxy-5-phenylpent-1-en-1-yl)cyclopentyl]hept-5-enoic acid
EINECS	Contact for details

Quality Control

Our (Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-((E)-(S)-3-Hydroxy-5-Phenyl-Pent-1-Enyl)-Cyclopentyl]-Hept-5-Enoic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and stereochemical identity verification, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at controlled room temperature (15-25°C) or as specified on the label or COA. This compound is light-sensitive and easily oxidized; prolonged exposure to air, light, or elevated temperatures should be avoided to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.