Description

4''''-o-Deacetyl-3'''-o-[3-C-Methyl-4-o-(2-Methyl-1-Oxopropyl)-2,6-Dideoxy-α-L-Arabino-Hexopyranosyl]-7-Methylolivomycin D is a structurally complex, semi-synthetic derivative of the olivomycin family of antibiotics, valued for its potent biological activity. This compound is a critical intermediate and reference standard in advanced pharmaceutical research and development, particularly for investigating novel anti-tumor agents and studying structure-activity relationships. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and manufacturers of high-purity active pharmaceutical ingredients (APIs) focused on oncology and infectious disease therapeutics.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel, more potent olivomycin analogs for anti-cancer drug discovery programs.
• Biochemical Research: Used as a reference standard and tool compound in molecular biology and pharmacology to study DNA intercalation and inhibition of topoisomerase II.
• API Development: Employed in the research and process development stages for creating new Active Pharmaceutical Ingredients (APIs) targeting specific cancers.
• Quality Control & Analytical Standards: Essential for HPLC, LC-MS, and NMR method development and validation to ensure purity and identity in related compound manufacturing.
• Academic Research: Utilized in university and institutional labs for fundamental studies on antibiotic mechanisms and the chemical modification of natural products.

Basic Information

Product Name	4''''-o-Deacetyl-3'''-o-[3-C-Methyl-4-o-(2-Methyl-1-Oxopropyl)-2,6-Dideoxy-α-L-Arabino-Hexopyranosyl]-7-Methylolivomycin D
CAS No.	37847-80-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	7-Methylolivomycin D derivative; Olivomycin A derivative; 4''''-Deacetyl-3'''-ester of Olivomycin; 7-Methyl-olivomycin D 4''''-deacetyl-3'''-ester; Antibiotic U-29479 derivative; 3'-O-(3-C-Methyl-4-O-isobutyryl-2,6-dideoxy-α-L-arabino-hexopyranosyl)-7-methylolivomycin D; 4''''-Deacetyl-3'''-O-[3-C-methyl-4-O-(2-methylpropanoyl)-2,6-dideoxy-α-L-arabino-hexopyranosyl]-7-methylolivomycin D
EINECS	Contact for details

Quality Control

Our 4''''-o-Deacetyl-3'''-o-[3-C-Methyl-4-o-(2-Methyl-1-Oxopropyl)-2,6-Dideoxy-α-L-Arabino-Hexopyranosyl]-7-Methylolivomycin D is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This compound is light-sensitive and easily oxidized; for long-term storage, consider under an inert atmosphere (e.g., nitrogen or argon) to maintain stability and potency. Keep the container in a dry, well-ventilated place.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.