Description

Antipain Hydrochloride Dihydrate is a potent and specific protease inhibitor widely used in biochemical and pharmaceutical research. This compound is critical for studying cellular processes involving serine and cysteine proteases, providing valuable insights into enzyme mechanisms and signaling pathways. It is an essential research-grade reagent for scientists in the fields of molecular biology, cell biology, and drug discovery, where precise enzyme inhibition is required.

Application

• Biochemical Research: Used as a specific inhibitor of trypsin, papain, and other serine/cysteine proteases in enzymatic assays.
• Cell Biology Studies: Employed to inhibit proteolytic activity in cell lysates and tissue extracts to preserve protein integrity.
• Pharmaceutical Development: Serves as a reference standard and tool compound in the discovery of novel protease-targeted therapeutics.
• Diagnostic Reagent Manufacturing: A key component in the formulation of diagnostic kits that require controlled protease activity.
• Academic Research: Utilized in university and institutional labs for fundamental research on protein degradation and regulation.

Basic Information

Product Name	Antipain Hydrochloride Dihydrate
CAS No.	37691-11-5
Molecular Formula	C27H44N10O6 • 2HCl • 2H2O
Molecular Weight	677.6 g/mol
Synonyms	Antipain Dihydrochloride Dihydrate; N-(4-Chlorophenyl)-N'-[2-(4-fluorophenyl)ethyl]urea; Protease Inhibitor Antipain; [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-Arg-L-Val-Arginal Dihydrochloride Dihydrate; Antipain HCl Dihydrate; NSC 326223; Arginylvalylargininal Dihydrochloride Dihydrate
EINECS	Contact for details

Quality Control

Our Antipain Hydrochloride Dihydrate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and verification of water content. Certificates of Analysis (COA) detailing all specifications are provided to ensure compliance with research-grade standards and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive (store away from light). For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	5.0 - 8.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.5%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.