Description

Antipain, Dihydrochloride is a potent and specific protease inhibitor belonging to the class of peptide aldehyde inhibitors. This compound is critical for researchers and manufacturers requiring precise control over proteolytic activity in biological systems. It is primarily utilized in biochemical research, pharmaceutical development, and as a key reagent in enzymatic studies to prevent unwanted protein degradation.

Application

• Biochemical Research: Used as a specific inhibitor of serine and cysteine proteases like trypsin, papain, and cathepsins in experimental protocols.
• Pharmaceutical Development: Employed in drug discovery and development processes to study protease-related pathways and validate therapeutic targets.
• Cell Culture & Protein Purification: Added to cell lysates and purification buffers to maintain protein integrity by inhibiting endogenous proteases.
• Diagnostic Reagent Manufacturing: Serves as a component in the formulation of diagnostic kits and assays that require stabilized enzyme activity.
• Enzymology Studies: A fundamental tool for kinetic studies and mechanistic analysis of various proteolytic enzymes.
• Academic & Industrial R&D: Essential for basic and applied research in molecular biology, biotechnology, and life sciences.

Basic Information

Product Name	Antipain, Dihydrochloride
CAS No.	37682-72-7
Molecular Formula	C27H44N10O6 · 2HCl
Molecular Weight	677.6 g/mol (as dihydrochloride salt)
Synonyms	Antipain 2HCl; N-(N-Carboxycarbonylphenylalanylphenylalanyl)argininal Dihydrochloride; [(S)-1-Carboxy-2-phenylethyl]carbamoyl-L-phenylalanyl-L-argininal Dihydrochloride; Protease Inhibitor Antipain; Antipain (microbial); Argininal, N2-[(N-carboxycarbonyl-L-phenylalanyl)-L-phenylalanyl]-, dihydrochloride
EINECS	Contact for details

Quality Control

Our Antipain, Dihydrochloride is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and tests for residual solvents and moisture content. Certificates of Analysis (COA) documenting full specifications are provided to ensure traceability and compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Potency (Enzymatic Assay)	≥ 90%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.