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15(R)-Prostaglandin F2Alpha CAS NO 37658-84-7


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CAS No.:37658-84-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

15(R)-Prostaglandin F2Alpha is a specific stereoisomer of a naturally occurring prostaglandin, a class of potent lipid compounds with significant biological activity. This high-purity compound is critical for advanced pharmaceutical research and development, particularly in studying receptor-specific interactions and metabolic pathways. It is primarily utilized by research institutions and pharmaceutical companies focused on developing novel therapeutics in areas such as reproductive health, ophthalmology, and inflammation.

Application

  • Pharmaceutical Reference Standard: Serves as a critical analytical standard for quality control and method development in drug manufacturing and regulatory submissions.
  • Biochemical Research: Used in vitro and in vivo studies to investigate the specific biological effects mediated by the 15(R) stereoisomer, including smooth muscle contraction and intraocular pressure regulation.
  • Drug Discovery & Development: A key intermediate or active pharmaceutical ingredient (API) precursor in the synthesis of novel prostaglandin-based therapeutics.
  • Cell Signaling Studies: Employed to study FP receptor activation and downstream signaling cascades in various cell culture models.
  • Ophthalmic Research: Investigated for potential applications in glaucoma treatment due to its effect on aqueous humor dynamics.

Basic Information

Product Name 15(R)-Prostaglandin F2Alpha
CAS No. 37658-84-7
Molecular Formula C₂₀H₃₄O₅
Molecular Weight 354.48 g/mol
Synonyms 15(R)-PGF2α; (15R)-Prostaglandin F2α; 15R-PGF2α; 9α,11α,15R-Trihydroxyprosta-5Z,13E-dien-1-oic acid; 15-epi-Prostaglandin F2α; 15R-Prostaglandin F2α; PGF2α (15R-isomer); 15(R)-PGF2alpha
EINECS Contact for details

Quality Control

Our 15(R)-Prostaglandin F2Alpha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and stereochemical integrity. We provide Certificates of Analysis (COA) with detailed chromatographic data and are committed to meeting the stringent requirements of research and cGMP-grade material production.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance White to off-white solid
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 98.0%
Specific Rotation Contact for details
Water Content (KF) ≤ 1.0%
Residue on Ignition ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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