Description

R(-)-Fenfluramine Hcl is the single enantiomer form of the pharmaceutical compound fenfluramine hydrochloride. This specific stereoisomer is of significant interest in advanced pharmaceutical research and development due to its targeted pharmacological activity. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) therapeutics and as a critical reference standard for analytical purposes.

Application

• Pharmaceutical Reference Standard: Serves as a high-purity calibrant for quality control and analytical method development in pharmaceutical laboratories.
• Neuropharmacology Research: Used in preclinical studies to investigate serotoninergic mechanisms and related neurological pathways.
• Active Pharmaceutical Ingredient (API) Intermediate: Acts as a key chiral building block in the synthesis of specialized therapeutic agents.
• Metabolite Studies: Employed in the research of drug metabolism and pharmacokinetics (DMPK) for related compounds.
• Analytical Method Development: Critical for developing and validating chromatographic (e.g., HPLC, LC-MS) methods for enantiomeric separation and quantification.

Basic Information

Product Name	R(-)-Fenfluramine Hcl
CAS No.	37577-24-5
Molecular Formula	C12H17ClF3N
Molecular Weight	267.72 g/mol
Synonyms	(-)-Fenfluramine Hydrochloride; (R)-Fenfluramine HCl; (3R)-N-Ethyl-α-methyl-3-(trifluoromethyl)benzenethanamine Hydrochloride; Dexfenfluramine Impurity; R-(-)-1-(3-Trifluoromethylphenyl)-2-ethylaminopropane Hydrochloride; (R)-1-[3-(Trifluoromethyl)phenyl]-2-(ethylamino)propane Hydrochloride; R(-)-Fenfluramine Hydrochloride
EINECS	Contact for details

Quality Control

Our R(-)-Fenfluramine Hcl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assay and impurity profiling, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) providing batch-specific data is available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Enantiomeric Excess)	≥99.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.