Description

9-Oxo-11Alpha,15S-Dihydroxy-Prosta-5Z,13E-Dien-1-Oic Acid, 2,3-Dihydroxypropyl Ester is a chemically modified prostaglandin derivative, specifically a glyceryl ester, valued for its enhanced stability and bioavailability compared to its parent acid form. This compound serves as a critical advanced pharmaceutical intermediate and a key reference standard in research and development. It is primarily required by manufacturers and research institutions in the pharmaceutical, biotechnology, and life sciences sectors for the synthesis and analytical validation of prostaglandin-based therapeutics.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of prostaglandin analog drugs targeting ocular hypertension, glaucoma, and other therapeutic areas.
• Reference Standard: Used as a certified reference material (CRM) for quality control, method validation, and regulatory compliance in analytical laboratories.
• Biochemical Research: Employed in pharmacological studies to investigate prostaglandin receptor activity, signal transduction pathways, and metabolic processes.
• Drug Discovery & Development: Serves as a precursor or model compound in the R&D of new anti-inflammatory, cardiovascular, and gastrointestinal agents.
• Analytical Chemistry: Utilized as an internal standard or calibrant in chromatographic (HPLC, GC) and spectroscopic analyses for accurate quantification.

Basic Information

Product Name	9-Oxo-11Alpha,15S-Dihydroxy-Prosta-5Z,13E-Dien-1-Oic Acid, 2,3-Dihydroxypropyl Ester
CAS No.	37497-47-5
Molecular Formula	C24H40O7
Molecular Weight	440.57 g/mol
Synonyms	11α,15S-Dihydroxy-9-oxoprosta-5Z,13E-dien-1-oic Acid 2,3-Dihydroxypropyl Ester; Prostaglandin E2 Glyceryl Ester; PGE2-G; Glyceryl Prostaglandin E2; 9-Keto-11α,15-dihydroxy-prosta-5,13-dien-1-oic Acid 2,3-Dihydroxypropyl Ester; (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic Acid 2,3-Dihydroxypropyl Ester; 37497-47-5
EINECS	Contact for details

Quality Control

Our 9-Oxo-11Alpha,15S-Dihydroxy-Prosta-5Z,13E-Dien-1-Oic Acid, 2,3-Dihydroxypropyl Ester is produced and tested under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your regulatory and quality assurance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. This product is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.