Description

20-Ethyl Prostaglandin E2 is a synthetic analog of the naturally occurring prostaglandin E2 (PGE2), modified with an ethyl group at the C-20 position to enhance its metabolic stability and biological activity. This compound is a potent bioactive lipid mediator with significant research and potential therapeutic value, primarily due to its role in modulating inflammation, smooth muscle contraction, and cellular proliferation. It is an essential biochemical tool for researchers and developers in the pharmaceutical and life sciences sectors, particularly those focused on inflammation pathways, reproductive health, and oncology research.

Application

• Biochemical Research: A critical reference standard and active agent for studying prostaglandin receptors (EP1-EP4), signal transduction pathways, and the role of eicosanoids in physiological and pathological processes.
• Pharmaceutical Development: Serves as a key intermediate or active pharmaceutical ingredient (API) in the development of novel therapeutics targeting inflammation, pain, cardiovascular diseases, and gastrointestinal disorders.
• Cell Culture & In Vitro Studies: Used to investigate its effects on cell growth, differentiation, and apoptosis in various cancer cell lines and primary cell cultures.
• Reproductive Biology: Employed in research related to uterine contractility, cervical ripening, and other reproductive processes where PGE2 analogs play a crucial role.
• Veterinary Medicine: Potential application in veterinary pharmaceuticals for estrus synchronization and the treatment of certain reproductive conditions in livestock.

Basic Information

Item	Detail
Product Name	20-Ethyl Prostaglandin E2
CAS No.	37492-24-3
Molecular Formula	C22H36O5
Molecular Weight	380.52 g/mol
Synonyms	20-Ethyl-PGE2; 20-Ethyl Prostaglandin E2; 11α,15α-Dihydroxy-20-ethyl-9-oxoprosta-5,13-dien-1-oic acid; 20-Ethyl dinoprostone; 20-Ethyl PGE2; Prostaglandin E2 20-ethyl; 20-Ethylprostaglandin E2
EINECS	Contact for details

Quality Control

Every batch of 20-Ethyl Prostaglandin E2 is manufactured and analyzed under strict quality management systems. We provide comprehensive analytical documentation to support your research and development needs. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for each lot. Our quality commitment ensures the material meets the high standards required for pharmaceutical research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is light-sensitive and easily oxidized. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.