Description

Cytochalasin CAS NO 37187-49-8 is a potent cell-permeable mycotoxin and a critical biochemical tool used to disrupt actin polymerization in cellular processes. This compound is essential for researchers and manufacturers in life sciences who require precise control over cytoskeletal dynamics for their work. It is primarily utilized in cell biology research, pharmaceutical development, and as a standard in biochemical assays.

Application

• Cell Biology Research: Used to inhibit actin filament polymerization, facilitating studies on cell motility, cytokinesis, and membrane dynamics.
• Pharmaceutical Development: Serves as a reference standard and a tool compound in drug discovery programs targeting the cytoskeleton.
• Cancer Research: Employed to investigate the role of actin in tumor cell invasion, metastasis, and apoptosis.
• Microbiology Studies: Acts as a model mycotoxin for studying fungal pathogenicity and host-cell interactions.
• Biochemical Assays: Utilized as a critical reagent in in vitro assays to study actin-myosin interactions and other cytoskeletal functions.
• Developmental Biology: Applied in studies of embryogenesis and morphogenesis where actin dynamics are crucial.

Basic Information

Product Name	Cytochalasin
CAS No.	37187-49-8
Molecular Formula	C₂₉H₃₇NO₅
Molecular Weight	479.61 g/mol
Synonyms	Cytochalasin B; Phomin; NSC 209017; 7-Oxabicyclo[4.3.0]nonane, 8,9-didehydro-4,5-epoxy-3,5-dihydroxy-10-phenyl-9-(2-methylpropyl)-, (3S,4S,5R,8R,9R,10S)-; [3S-(3α,4β,5α,8β,9α,10α)]-8,9-Didehydro-4,5-epoxy-3,5-dihydroxy-10-phenyl-9-(2-methylpropyl)-7-oxabicyclo[4.3.0]nonane; Helminthosporium dematioideum metabolite
EINECS	253-366-2

Quality Control

Our Cytochalasin is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry, cool place. This product is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to air and humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.