Description

Benzenepropanal, α-Fluoro-4-Methyl-β-Oxo- (9Ci) is a specialized fluorinated aromatic building block with a reactive β-keto aldehyde structure. This compound is valued for its role as a versatile intermediate in advanced organic synthesis, enabling the introduction of both fluorine and a functionalized side chain into target molecules. It is primarily needed by research and development chemists and process scale-up teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key synthon for the development of fluorinated drug candidates, particularly in protease inhibitors and kinase-targeted therapies.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and stability.
• Material Science Research: Serves as a precursor for synthesizing novel fluorinated organic materials and liquid crystals.
• Chemical Biology Probes: Employed in the design and synthesis of fluorinated probes and tags for studying biological mechanisms.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed and other metal-mediated coupling reactions to construct complex aromatic systems.
• Asymmetric Synthesis: Utilized as a chiral building block or precursor for enantioselective synthesis of bioactive molecules.

Basic Information

Product Name	Benzenepropanal, α-Fluoro-4-Methyl-β-Oxo- (9Ci)
CAS No.	37032-37-4
Molecular Formula	C10H9FO2
Molecular Weight	180.18 g/mol
Synonyms	4-Methyl-α-fluoro-β-oxobenzenepropanal; 2-Fluoro-3-(4-methylbenzoyl)propanal; 3-(4-Methylphenyl)-2-fluoro-3-oxopropanal; α-Fluoro-4-methyl-β-oxobenzenepropanal; 37032-37-4; 4-Methylbenzoylacetaldehyde, 2-fluoro-; FCH2C(O)CH2C(O)C6H4CH3-p
EINECS	Contact for details

Quality Control

Our Benzenepropanal, α-Fluoro-4-Methyl-β-Oxo- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its light-sensitive nature and reactivity as a fluoride/strong alkali-sensitive compound, the container must be kept sealed under an inert atmosphere if specified for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.