Description

2-Trifluoromethyl-Benzalmalononitrile is a specialized organic compound featuring a benzalmalononitrile core substituted with a trifluoromethyl group. This molecular structure makes it a valuable building block and intermediate in advanced chemical synthesis, particularly for introducing the trifluoromethyl moiety, which is prized for its ability to modulate the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the CF₃ group enhances biological activity.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and organic electronic materials with unique properties.
• Chemical Synthesis: Acts as a versatile reagent in organic chemistry for cyclization reactions and the construction of complex heterocyclic compounds like pyridines and pyrimidines.
• Fluorine Chemistry Studies: An important compound for academic and industrial research focused on incorporating fluorine atoms into organic molecules.

Basic Information

Product Name	2-Trifluoromethyl-Benzalmalononitrile
CAS No.	36937-89-0
Molecular Formula	C₁₁H₅F₃N₂
Molecular Weight	222.17 g/mol
Synonyms	2-(2-(Trifluoromethyl)benzylidene)malononitrile; α-(2-Trifluoromethylbenzylidene)malononitrile; (2-Trifluoromethylbenzylidene)propanedinitrile; 2-[(2-Trifluoromethylphenyl)methylene]malononitrile; Benzeneacetonitrile, α-[(trifluoromethyl)methylene]-, α-(2-trifluoromethylbenzylidene)malononitrile; 2-Trifluoromethylbenzalmalononitrile
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-Benzalmalononitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for our global B2B partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light exposure to maintain stability and purity. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.