Description

Deoxyharringtonine is a naturally occurring alkaloid derived from the *Cephalotaxus* genus. This compound is a key intermediate and structural analog of the potent anti-leukemic agent, Harringtonine, making it a critical building block for pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for the synthesis of novel therapeutic agents and in-depth pharmacological studies.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of Harringtonine and related anti-cancer compounds.
• Biochemical Research: Used as a reference standard and investigative tool in studies of protein synthesis inhibition and apoptosis.
• Oncology Drug Discovery: A key scaffold for developing and screening new chemotherapeutic agents targeting hematologic malignancies.
• Academic Research: Employed in university and institutional labs for pharmacological and mechanistic studies of cephalotaxus alkaloids.
• Standards and Metrology: Provides a high-purity standard for analytical method development and quality control in pharmaceutical manufacturing.

Basic Information

Product Name	Deoxyharringtonine
CAS No.	36804-95-2
Molecular Formula	C28H37NO8
Molecular Weight	515.60 g/mol
Synonyms	Deoxyharringtonine; Isoharringtonine; NSC 32946; Homodeoxyharringtonine; (2'R,3'R)-3'-Phenyl-2',3'-dihydro-2'-hydroxy-2'-(hydroxymethyl)cephalotaxine; Cephalotaxine, 2-hydroxy-2-(hydroxymethyl)-3-phenyl-, (2R,3R)-
EINECS	Contact for details

Quality Control

Our Deoxyharringtonine is produced and tested under strict quality management systems. Each batch undergoes comprehensive analysis to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research intermediates. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.