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(2-Chlorophenyl)Magnesium Bromide CAS NO 36692-27-0
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CAS No.:36692-27-0
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(2-Chlorophenyl)Magnesium Bromide is a versatile organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry for the formation of carbon-carbon bonds. Its value lies in its ability to act as a nucleophile, introducing the 2-chlorophenyl moiety into target molecules with high efficiency and selectivity. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise functionalization of complex organic structures.
Application
- Pharmaceutical Intermediate Synthesis: Key building block for constructing active pharmaceutical ingredients (APIs), particularly those containing biphenyl or substituted phenyl rings.
- Agrochemical Production: Used in the synthesis of herbicides, fungicides, and insecticides where the 2-chlorophenyl group confers specific biological activity.
- Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
- Material Science Research: Employed in the development of organic electronic materials, liquid crystals, and polymers requiring specific aromatic units.
- Fine Chemical Manufacturing: Facilitates the production of complex fragrance and flavor compounds through controlled aryl addition reactions.
- Academic & R&D Laboratories: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry.
Basic Information
| Product Name | (2-Chlorophenyl)Magnesium Bromide |
| CAS No. | 36692-27-0 |
| Molecular Formula | C6H4ClMgBr |
| Molecular Weight | 215.75 g/mol |
| Synonyms | 2-Chlorophenylmagnesium Bromide; o-Chlorophenylmagnesium Bromide; Magnesium, bromo(2-chlorophenyl)-; (2-Chlorophenyl)magnesium Bromide solution; Grignard Reagent (2-Chlorophenyl); Bromo(2-chlorophenyl)magnesium; o-Chloro-phenylmagnesium bromide |
| EINECS | Contact for details |
Quality Control
Our (2-Chlorophenyl)Magnesium Bromide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Quality is assured through rigorous analytical testing, including titration for concentration and GC analysis for purity and solvent composition. A comprehensive Certificate of Analysis (COA) detailing concentration, assay, and impurity profiles is provided with each shipment to support your quality management systems.
Storage
Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This material is highly volatile, easily oxidized, and reacts violently with water and protic solvents. Keep away from heat, sparks, open flames, and strong oxidizing agents. Use only in a certified fume hood with appropriate personal protective equipment.
Specification
| Item | Specification |
|---|---|
| Appearance | Clear, colorless to light brown solution |
| Concentration (in THF or Ether) | 0.5 M - 2.0 M (Custom concentrations available) |
| Assay (by Titration) | ≥ 95% |
| Identification (IR/NMR) | Conforms to structure |
| Solvent (Typical) | Tetrahydrofuran (THF) or Diethyl Ether |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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