Description

1-Fluoro-2,4-Bis-Trifluoromethyl-Benzene is a high-value fluorinated aromatic building block characterized by its unique electron-deficient benzene ring. This compound matters for its role as a critical intermediate in the synthesis of advanced materials and active pharmaceutical ingredients (APIs), where its trifluoromethyl and fluorine substituents impart desirable properties like enhanced lipophilicity and metabolic stability. Industries such as agrochemicals, pharmaceuticals, and specialty polymers need this chemical for developing next-generation products with improved performance characteristics.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in antiviral and anticancer research.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and stability.
• Specialty Polymer Monomer: Incorporated into high-performance polymers to increase chemical resistance, thermal stability, and reduce surface energy.
• Catalyst Ligand Precursor: Utilized in the synthesis of sophisticated ligands for catalysis in fine chemical manufacturing.
• Organic Synthesis Building Block: Employed in nucleophilic aromatic substitution and cross-coupling reactions to introduce fluorinated aryl groups.

Basic Information

Product Name	1-Fluoro-2,4-Bis-Trifluoromethyl-Benzene
CAS No.	36649-94-2
Molecular Formula	C9H3F7
Molecular Weight	232.11 g/mol
Synonyms	2,4-Bis(trifluoromethyl)fluorobenzene; 1-Fluoro-2,4-bis(trifluoromethyl)benzene; α,α,α,α',α',α'-Hexafluoro-2-fluoro-m-xylene; 2-Fluoro-α,α,α,α',α',α'-hexafluoro-m-xylene; Benzene, 1-fluoro-2,4-bis(trifluoromethyl)-; 2,4-Di(trifluoromethyl)fluorobenzene; F-2,4-Bis(CF3)-Benzene
EINECS	Contact for details

Quality Control

Our 1-Fluoro-2,4-Bis-Trifluoromethyl-Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	≤ 2.0% total
Density (at 20°C)	~1.55 g/mL
Refractive Index (n20/D)	~1.38

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.