Description

4-(2-Tetrahydro-2H-Pyranoxy)Phenylmagnesium Bromide is a specialized organometallic reagent, specifically a Grignard reagent, widely used in advanced organic synthesis. This compound is valued for its ability to introduce the 4-(2-tetrahydropyranyloxy)phenyl group into target molecules, enabling the construction of complex chemical architectures. It is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, facilitating the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of compounds with complex aromatic ether functionalities.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and plant growth regulators that require specific phenyl ether structures.
• Liquid Crystal & OLED Material Precursor: Serves as a crucial reagent in the synthesis of organic semiconductors and liquid crystal molecules for display technologies.
• Polymer & Specialty Chemical Manufacturing: Employed to create monomers and functionalized polymers with tailored properties for high-performance materials.
• Academic & Contract Research: Essential tool for methodology development and complex molecule construction in research laboratories and CROs (Contract Research Organizations).
• Fine Chemical Production: Facilitates the synthesis of complex fragrances, flavors, and other high-value specialty chemicals.

Basic Information

Product Name	4-(2-Tetrahydro-2H-Pyranoxy)Phenylmagnesium Bromide
CAS No.	36637-44-2
Molecular Formula	C11H13BrMgO2
Molecular Weight	281.43 g/mol
Synonyms	4-(2-Tetrahydropyranyloxy)phenylmagnesium bromide; [4-(Oxan-2-yloxy)phenyl]magnesium bromide; 4-(2H-Pyran-2-yloxy)phenylmagnesium bromide; (4-((Tetrahydro-2H-pyran-2-yl)oxy)phenyl)magnesium bromide; THP-Protected Hydroxyphenylmagnesium Bromide; Grignard Reagent of 4-(2-THP-oxy)benzene; 4-(2-THP-O)C6H4MgBr
EINECS	Contact for details

Quality Control

Our production of 4-(2-Tetrahydro-2H-Pyranoxy)Phenylmagnesium Bromide adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is analyzed to confirm identity, purity, and concentration (typically supplied as a solution in THF or diethyl ether). A comprehensive Certificate of Analysis (COA) detailing assay (by titration), residual solvents, and other critical parameters is provided with every shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. This reagent is typically supplied and stored as a solution under an inert atmosphere (argon or nitrogen) to prevent degradation. Store the sealed container in a cool, dry, well-ventilated area, away from heat, moisture, and incompatible materials. Due to its pyrophoric nature in concentrated form, handle only under an inert atmosphere using appropriate techniques.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Identification (IR)	Conforms to structure
Assay (Titration)	0.5 M in THF or as specified
Purity (HPLC)	≥ 95% (by GC/HPLC of derived product)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.