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9-Oxo-15S-Hydroxy-Prosta-5Z,10,13E,17Z-Tetraen-1-Oic Acid CAS NO 36614-31-0


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CAS No.:36614-31-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

9-Oxo-15S-Hydroxy-Prosta-5Z,10,13E,17Z-Tetraen-1-Oic Acid is a high-purity prostaglandin analog and a key synthetic intermediate in advanced pharmaceutical research. This compound is critical for the development and study of bioactive lipid mediators that regulate inflammation, immune response, and cellular signaling pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents, particularly in the fields of immunology, oncology, and metabolic disease research.

Application

  • Pharmaceutical Intermediate: A crucial building block for the synthesis of advanced prostaglandin-based drugs and experimental therapeutics.
  • Biochemical Research: Used as a reference standard and precursor in studies of eicosanoid signaling pathways, inflammation, and cellular metabolism.
  • Drug Discovery & Development: Serves as a key starting material in medicinal chemistry programs targeting prostaglandin receptors (e.g., EP, DP, FP receptors).
  • Academic Research: Employed in university and institutional labs for investigating the physiological and pathological roles of prostanoids.
  • Standards & Calibration: Used to prepare analytical standards for quality control and quantification in complex biological matrices via HPLC or LC-MS.

Basic Information

Product Name 9-Oxo-15S-Hydroxy-Prosta-5Z,10,13E,17Z-Tetraen-1-Oic Acid
CAS No. 36614-31-0
Molecular Formula C₂₀H₃₀O₄
Molecular Weight 334.45 g/mol
Synonyms 15(S)-HETE; 15S-Hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic Acid; 15(S)-HETE; 15S-Hydroxyeicosatetraenoic Acid; 15(S)-Hydroxy-5,8,11,13-eicosatetraenoic Acid; 15S-HETE-d8 (unlabeled parent compound); (15S)-15-Hydroxy-5Z,8Z,11Z,13E-eicosatetraenoic Acid; 15-HETE (S-isomer)
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Quality Control

Our 9-Oxo-15S-Hydroxy-Prosta-5Z,10,13E,17Z-Tetraen-1-Oic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the stringent requirements of research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere. Allow the sealed container to reach room temperature before opening to prevent moisture condensation. Keep away from strong oxidizers and bases.

Specification

Item Specification
Appearance Colorless to pale yellow oil or solid
Identification (HPLC) Conforms to reference standard
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95% (Area %)
Isomeric Purity (S-isomer) ≥ 98%
Solubility Soluble in ethanol, DMSO, DMF; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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