Description

1,2,3-Trichloro-4-Fluorobenzene is a halogenated aromatic compound that serves as a versatile and critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable precursor for the development of complex molecules, particularly in the agrochemical and pharmaceutical sectors. This intermediate is essential for researchers and manufacturers requiring a reliable source of high-purity fluorinated and chlorinated benzene derivatives for creating active ingredients and functional materials.

Application

• Agrochemical Intermediate: A key synthon in the synthesis of novel herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic cores.
• Liquid Crystal & Electronic Chemicals: Acts as a starting material for the production of fluorinated liquid crystals and other electronic-grade specialty chemicals.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce functional groups.
• Dye & Pigment Manufacturing: Serves as a precursor in the synthesis of complex halogenated dyes and organic pigments.
• Polymer Modification: Used to incorporate halogenated phenyl groups into polymer chains to alter properties like flame retardancy and stability.

Basic Information

Product Name	1,2,3-Trichloro-4-Fluorobenzene
CAS No.	36556-36-2
Molecular Formula	C6H2Cl3F
Molecular Weight	199.44 g/mol
Synonyms	4-Fluoro-1,2,3-trichlorobenzene; 1,2,3-Trichloro-4-fluorobenzene; 3,4,5-Trichlorofluorobenzene; Benzene, 1,2,3-trichloro-4-fluoro-; NSC 88279; 4-Fluoro-1,2,3-trichlorobenzol; Fluorobenzene, 2,3,4-trichloro-
EINECS	Contact for details

Quality Control

Our 1,2,3-Trichloro-4-Fluorobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC)	Individual impurity ≤ 1.0%
Density (at 20°C)	~1.7 g/cm³
Boiling Point	~210-215 °C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.