Description

4-Methoxyphenethylmagnesium Bromide is a highly reactive Grignard reagent, a cornerstone organometallic compound for advanced organic synthesis. Its value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the construction of complex molecular architectures. This reagent is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to synthesize novel compounds and active ingredients.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the 4-methoxyphenethyl moiety into target molecules during the research and development of new drug candidates.
• Agrochemical Manufacturing: Used in the synthesis of advanced pesticides and herbicides, where the methoxyphenethyl group can contribute to biological activity.
• Fine Chemical Production: Employed in the creation of specialty chemicals, flavors, fragrances, and advanced materials requiring specific aryl-alkyl linkages.
• Academic & Industrial R&D: Serves as a fundamental tool in organic chemistry laboratories for methodological studies and the exploration of new synthetic pathways.
• Nucleophilic Addition Reactions: Primarily used for additions to carbonyl compounds (aldehydes, ketones, esters) to form secondary or tertiary alcohols.
• Cross-Coupling Precursor: Can be utilized in transition-metal catalyzed cross-coupling reactions after transmetalation.

Basic Information

Product Name	4-Methoxyphenethylmagnesium Bromide
CAS No.	36278-54-3
Molecular Formula	C9H11BrMgO
Molecular Weight	239.39 g/mol
Synonyms	2-(4-Methoxyphenyl)ethylmagnesium Bromide; p-Methoxyphenethylmagnesium Bromide; (4-Methoxyphenethyl)magnesium Bromide; 4-Methoxybenzeneethanemagnesium Bromide; Magnesium, bromo[2-(4-methoxyphenyl)ethyl]-; Grignard Reagent, 4-Methoxyphenethylmagnesium Bromide; Bromo(4-methoxyphenethyl)magnesium
EINECS	Contact for details

Quality Control

Our 4-Methoxyphenethylmagnesium Bromide is manufactured and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot undergoes comprehensive analysis, including titration to determine concentration and purity assessment. A Certificate of Analysis (COA) detailing all relevant specifications is provided with every shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent degradation. This compound is highly volatile, easily oxidized, and reacts violently with water and protic solvents; handle and store accordingly in a cool, dry, well-ventilated area away from incompatible materials.

Specification

Item	Specification
Appearance	Clear to slightly colored solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.