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Prostaglandins E2 Methyl Ester CAS NO 36210-00-1


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CAS No.:36210-00-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Prostaglandins E2 Methyl Ester CAS NO 36210-00-1 is a chemically modified derivative of Prostaglandin E2 (PGE2), a key bioactive lipid mediator. This methyl ester form offers enhanced stability and handling properties for research and development applications, serving as a critical intermediate in the synthesis of more complex prostaglandin analogs. It is primarily utilized by pharmaceutical researchers, fine chemical manufacturers, and academic institutions engaged in the study of inflammation, reproductive biology, and cellular signaling pathways.

Application

  • Pharmaceutical Intermediate: A key building block in the synthesis of novel prostaglandin-based therapeutics targeting various physiological processes.
  • Biochemical Research: Used as a stable analog in studies investigating prostaglandin receptor binding, signal transduction mechanisms, and metabolic pathways.
  • Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
  • Fine Chemical Synthesis: An important precursor for the preparation of specialized prostaglandin derivatives with tailored biological activity.
  • Cell Culture & In Vitro Studies: Employed in laboratory settings to study the effects of prostaglandin signaling on cell proliferation, differentiation, and inflammatory responses.

Basic Information

Product Name Prostaglandins E2 Methyl Ester
CAS No. 36210-00-1
Molecular Formula C21H34O5
Molecular Weight 366.50 g/mol
Synonyms PGE2 Methyl Ester; Dinoprostone Methyl Ester; (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid Methyl Ester; Methyl (5Z,11α,13E,15S)-11,15-dihydroxy-9-oxoprosta-5,13-dien-1-oate; Prostaglandin E2 ME; PGE2-ME; U-12062
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Quality Control

Our Prostaglandins E2 Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and synthesis. A Certificate of Analysis (COA) detailing specific results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item Specification
Appearance White to off-white solid
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95.0%
Related Substances (HPLC) Total impurities ≤ 5.0%
Water Content (KF) ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.

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