Description

3-Bromo-2-Fluoropyridine is a high-purity halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both bromine and fluorine substituents, makes it an exceptionally versatile intermediate for introducing functional complexity into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry for creating fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the creation of novel organic electronic materials, liquid crystals, and functional polymers.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis and Scale-up: A fundamental starting material for contract research organizations (CROs) and custom synthesis manufacturers.

Basic Information

Product Name	3-Bromo-2-Fluoropyridine
CAS No.	36178-05-9
Molecular Formula	C5H3BrFN
Molecular Weight	175.99 g/mol
Synonyms	2-Fluoro-3-bromopyridine; 3-Bromo-2-fluoropyridine; 2-Fluoro-3-bromo-pyridine; Pyridine, 3-bromo-2-fluoro-; 3-Bromo-2-fluoro-pyridine; 3-Br-2-F-Pyridine
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Fluoropyridine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP or ISO 9001 frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials. The container must be kept tightly closed and stored in a dry atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.