Description

5-Trans Prostaglandin E2 is a synthetic analog of the naturally occurring prostaglandin E2, distinguished by the trans configuration of its 5,6-double bond. This structural modification offers enhanced stability for research and development applications where precise biological activity is required. It is a critical biochemical tool for researchers in the pharmaceutical and life sciences sectors, particularly for studying inflammation, smooth muscle contraction, and cellular signaling pathways.

Application

• Pharmaceutical Research & Development: A key reference standard and active pharmaceutical ingredient (API) intermediate for developing novel therapeutics targeting inflammation, pain, and reproductive health.
• Biochemical Research: Used as a potent ligand in receptor binding assays and cell signaling studies to investigate the role of prostaglandin receptors (EP receptors) in various physiological and pathological processes.
• Cell Culture & In Vitro Studies: Employed to modulate cellular functions, including studying its effects on vasodilation, uterine contraction, and gastrointestinal motility in experimental models.
• Analytical Standard: Serves as a high-purity certified reference material (CRM) for method development, validation, and quality control in analytical laboratories using HPLC, LC-MS, or GC-MS.
• Cosmeceutical Research: Investigated for potential applications in advanced skincare formulations targeting inflammation and cellular regeneration.

Basic Information

Product Name	5-Trans Prostaglandin E2
CAS No.	36150-00-2
Molecular Formula	C₂₀H₃₂O₅
Molecular Weight	352.47 g/mol
Synonyms	5-trans-PGE2; (5Z,13E)-(15S)-11,15-Dihydroxy-9-oxoprosta-5,13-dien-1-oic Acid; 5-trans-Prostaglandin E2; PGE2 (5-trans-isomer); trans-5-Prostaglandin E2; 5t-PGE2; 5-trans-PGE₂
EINECS	Contact for details

Quality Control

Our 5-Trans Prostaglandin E2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent high purity.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.