Description

4-Hydroxypropranolol Glycol is a key chemical intermediate and a metabolite of the β-blocker drug propranolol. This compound matters for its critical role in pharmaceutical research, development, and quality control processes. It is primarily needed by pharmaceutical manufacturers, analytical laboratories, and research institutions for use as a reference standard, in metabolic studies, and in the synthesis of more complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Reference Standard for analytical method development and validation.
• Metabolite in pharmacokinetic and drug metabolism studies.
• Key intermediate in the synthesis of propranolol analogs and derivatives.
• Impurity standard for quality control of propranolol API and related formulations.
• Biochemical research tool for studying β-adrenergic receptor pathways.
• Starting material for the preparation of isotopically labeled internal standards.

Basic Information

Product Name	4-Hydroxypropranolol Glycol
CAS No.	36112-96-6
Molecular Formula	C13H21NO3
Molecular Weight	239.31 g/mol
Synonyms	1-(Isopropylamino)-3-(4-hydroxyphenoxy)-2-propanol; 4-Hydroxypropranolol; 1-(4-Hydroxyphenoxy)-3-[(1-methylethyl)amino]-2-propanol; Propranolol, 4-hydroxy-; Propranolol glycol, 4-hydroxy-; 4-Hydroxypropranolol Diol; 4-OH-Propranolol Glycol
EINECS	Contact for details

Quality Control

Our 4-Hydroxypropranolol Glycol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.