Description

3-Pyridinemethanol, 5-Fluoro-, 1-Oxide (9Ci) is a specialized fluorinated pyridine derivative, a high-value intermediate in advanced organic synthesis. This compound matters for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the fluorine atom and N-oxide moiety are critical for modulating biological activity and physicochemical properties. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to innovate and scale new molecular entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of fluorinated drug candidates, particularly in oncology, central nervous system (CNS), and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine substituent enhances efficacy and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chiral ligands or metal-organic complexes used in asymmetric catalysis.
• Material Science Research: Employed in the development of specialty polymers, liquid crystals, or electronic materials that incorporate heterocyclic structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms or biological pathways.
• Custom Synthesis and Contract Manufacturing: A key building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	3-Pyridinemethanol, 5-Fluoro-, 1-Oxide (9Ci)
CAS No.	35865-30-6
Molecular Formula	C6H6FNO2
Molecular Weight	143.12 g/mol
Synonyms	5-Fluoro-3-pyridinemethanol 1-Oxide; (5-Fluoropyridin-3-yl)methanol N-Oxide; 5-Fluoro-3-(hydroxymethyl)pyridine 1-Oxide; 5-Fluoronicotinyl Alcohol N-Oxide; 3-Hydroxymethyl-5-fluoropyridine N-Oxide; 5-Fluoro-3-pyridylmethanol N-Oxide; 35865-30-6; 5-Fluoropyridine-3-methanol 1-Oxide
EINECS	Contact for details

Quality Control

Our 3-Pyridinemethanol, 5-Fluoro-, 1-Oxide is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request. We support compliance with cGMP and ICH Q7 guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.