Description

15(R)-15-Methyl Prostaglandin F2Alpha is a synthetic analog of the naturally occurring prostaglandin F2α, distinguished by a methyl group at the 15(R) position. This structural modification enhances its metabolic stability and biological activity, making it a valuable intermediate and reference standard in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on developing therapeutics for ophthalmology, reproductive health, and cardiovascular conditions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced prostaglandin-based drugs, particularly for glaucoma treatment and labor induction.
• Biochemical Research: Used as a potent reference standard and agonist in studies investigating FP receptor signaling pathways and cellular responses.
• Ophthalmic Drug Development: Serves as a critical precursor for developing novel intraocular pressure-lowering agents (anti-glaucoma medications).
• Veterinary Medicine: Applied in reproductive management protocols for livestock, such as estrus synchronization and parturition induction.
• Cell Culture & Toxicology Studies: Employed to study smooth muscle contraction, inflammatory processes, and cellular toxicity models.

Basic Information

Product Name	15(R)-15-Methyl Prostaglandin F2Alpha
CAS No.	35864-81-4
Molecular Formula	C₂₁H₃₄O₅
Molecular Weight	366.49 g/mol
Synonyms	15(R)-15-Methyl-PGF2α; 15-Methylprostaglandin F2α (15R-isomer); (5Z,9α,11α,13E,15R)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid; 15(R)-Methyl Prostaglandin F2 Alpha; 15R-15-Methyl Prostaglandin F2α; Travoprost Related Compound C (USP); 15-Methyl PGF2α; 15(R)-Me-PGF2α
EINECS	Contact for details

Quality Control

Our 15(R)-15-Methyl Prostaglandin F2Alpha is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.