Description

Tauroursodeoxycholic Acid Sodium Salt is a conjugated bile acid derivative with significant biochemical and pharmaceutical relevance. This compound is valued for its enhanced hydrophilicity and stability compared to its unconjugated counterparts, making it a critical component in advanced research and therapeutic formulations. It is primarily sought after by pharmaceutical manufacturers, research institutions, and biotechnology companies engaged in hepatology, metabolic studies, and the development of cytoprotective agents.

Application

• Pharmaceutical Intermediates: A key starting material or active pharmaceutical ingredient (API) in the synthesis of hepatoprotective and choleretic drugs.
• Biomedical Research: Utilized in cell culture and in vitro studies to investigate mechanisms of apoptosis, endoplasmic reticulum (ER) stress, and bile acid metabolism.
• Therapeutic Development: Serves as a reference standard and active component in formulations targeting cholestatic liver diseases, such as primary biliary cholangitis (PBC).
• Metabolic Studies: Employed as a tool compound to study the Farnesoid X receptor (FXR) and TGR5 receptor signaling pathways.
• Neuroprotective Research: Investigated for its potential role in mitigating neurodegenerative conditions by reducing cellular stress.
• Diagnostic Reagents: Used in the preparation of calibration standards for analytical methods quantifying bile acids in biological samples.

Basic Information

Product Name	Tauroursodeoxycholic Acid Sodium Salt
CAS No.	35807-85-3
Molecular Formula	C₂₆H₄₄NNaO₆S
Molecular Weight	521.69 g/mol
Synonyms	Tauroursodeoxycholate Sodium; Sodium Tauroursodeoxycholate; TUDCA Sodium Salt; Ursodoxicoltaurine Sodium Salt; 2-[[(3α,5β,7β)-3,7-Dihydroxy-24-oxocholan-24-yl]amino]ethanesulfonate Sodium Salt; UR-906; Taurolite; Tauroursodiol Sodium
EINECS	Contact for details

Quality Control

Our Tauroursodeoxycholic Acid Sodium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and stringent controls for related substances and residual solvents. Certificates of Analysis (COA) are provided, detailing compliance with in-house specifications developed for pharmaceutical research and development. We support our clients with full traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Water Content (KF)	≤5.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.