Description

Pyrimidine-2-Sulfonyl Fluoride is a high-purity, reactive sulfonyl fluoride derivative of the pyrimidine heterocycle. This compound serves as a critical building block in advanced organic synthesis, particularly for the development of pharmaceuticals and agrochemicals. It is primarily utilized by research institutions and fine chemical manufacturers engaged in medicinal chemistry and the creation of novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially sulfonamide-based drugs.
• Medicinal Chemistry: Used in high-throughput screening and the development of targeted covalent inhibitors for disease treatment.
• Agrochemical Research: Serves as a building block for creating novel herbicides, fungicides, and pesticides with specific modes of action.
• Chemical Biology Probe Development: Employed in activity-based protein profiling (ABPP) to study enzyme function and discover new drug targets.
• Material Science: Potential monomer or cross-linking agent in the synthesis of specialty polymers with unique properties.
• Organic Synthesis: Acts as a versatile electrophile for introducing the pyrimidine-2-sulfonyl moiety into complex molecular architectures.

Basic Information

Product Name	Pyrimidine-2-Sulfonyl Fluoride
CAS No.	35762-87-9
Molecular Formula	C4H3FN2O2S
Molecular Weight	162.14 g/mol
Synonyms	2-Pyrimidinesulfonyl fluoride; Pyrimidine-2-sulfonylfluoride; 2-Fluorosulfonylpyrimidine; 2-Pyrimidylsulfonyl fluoride; Pyrimidin-2-ylsulfonyl fluoride; 35762-87-9; 2-Pyrimidinesulfonic acid fluoride
EINECS	Contact for details

Quality Control

Our Pyrimidine-2-Sulfonyl Fluoride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and moisture content analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.