Description

4,6-Dimethyl-Pyrimidine-2-Sulfonyl Fluoride is a high-purity, specialized sulfonyl fluoride derivative, a key building block in modern synthetic chemistry. Its core value lies in its reactivity as a selective sulfonylation and fluorination agent, enabling the efficient synthesis of complex molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active ingredients and advanced intermediates.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially sulfonamide-based therapeutics and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the sulfonyl fluoride moiety contributes to biological activity.
• Chemical Biology & Proteomics: Serves as a reactive handle in activity-based protein profiling (ABPP) and the development of covalent inhibitors.
• Material Science Research: Employed in the creation of functionalized polymers and advanced materials with specific surface properties.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in metal-catalyzed reactions to form carbon-sulfur bonds.
• Fluorine Chemistry: A valuable source of the sulfonyl fluoride functional group for introducing fluorine into target molecules.

Basic Information

Product Name	4,6-Dimethyl-Pyrimidine-2-Sulfonyl Fluoride
CAS No.	35762-73-3
Molecular Formula	C6H7FN2O2S
Molecular Weight	190.20 g/mol
Synonyms	2-Pyrimidinesulfonyl fluoride, 4,6-dimethyl-; 4,6-Dimethyl-2-pyrimidinesulfonyl fluoride; 4,6-Dimethylpyrimidine-2-sulfonyl fluoride; 2-(Fluorosulfonyl)-4,6-dimethylpyrimidine; 4,6-Dimethyl-2-sulfonylfluoropyrimidine; 35762-73-3; 4,6-Dimethylpyrimidine-2-sulfonylfluoride
EINECS	Contact for details

Quality Control

Every batch of 4,6-Dimethyl-Pyrimidine-2-Sulfonyl Fluoride is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical applications. Our products undergo rigorous quality testing, including HPLC for purity and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.