Description

3-Acetyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7-sulfonyl chloride is a high-purity, specialized organic intermediate of significant importance in advanced chemical synthesis. This compound serves as a critical building block for the development of novel pharmacologically active molecules, particularly in medicinal chemistry research. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel benzazepine-based drug candidates, potentially targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Fine Chemical Synthesis: Serves as a reactive sulfonyl chloride component for introducing the sulfonamide moiety into complex molecular architectures.
• Agrochemical Development: Potential intermediate in the research and synthesis of new active ingredients for crop protection products.
• Chemical Biology Probes: Can be utilized to create labeled or tagged molecules for studying biological pathways and protein interactions.

Basic Information

Product Name	3-Acetyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7-sulfonyl chloride
CAS No.	35760-18-0
Molecular Formula	C12H14ClNO3S
Molecular Weight	287.76 g/mol
Synonyms	1H-Benzo[d]azepine-7-sulfonyl chloride, 2,3,4,5-tetrahydro-3-acetyl-; 3-Acetyl-2,3,4,5-tetrahydro-1H-1-benzazepine-7-sulfonyl chloride; 7-(Chlorosulfonyl)-3-acetyl-2,3,4,5-tetrahydro-1H-1-benzazepine; 3-Acetyl-1,2,3,4,5,6-hexahydro-3-benzazonine-7-sulfonyl chloride; 3-Acetyl-2,3,4,5-tetrahydrobenzo[b]azepine-7-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Acetyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7-sulfonyl chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.