Description

15(S)-15-Methyl Prostaglandin E2 is a synthetic analog of the naturally occurring prostaglandin E2, modified to enhance its stability and biological activity. This compound is a critical intermediate and research tool in the development of novel pharmaceuticals targeting inflammation, gastrointestinal disorders, and reproductive health. It is essential for pharmaceutical R&D laboratories, biotechnology companies, and advanced academic research institutions focused on prostaglandin-based therapeutics and signaling pathway studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of advanced prostaglandin-based drugs for ulcer treatment and ocular hypertension.
• Biochemical Research: Used as a potent and selective ligand to study EP receptor subtypes and their role in inflammatory and pain pathways.
• Cell Culture & Differentiation: Employed in stem cell research to induce specific differentiation pathways and modulate cellular responses.
• Veterinary Medicine: Applied in reproductive management and fertility treatments in livestock and companion animals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	15(S)-15-Methyl Prostaglandin E2
CAS No.	35700-27-7
Molecular Formula	C22H36O5
Molecular Weight	380.52 g/mol
Synonyms	15(S)-15-Methyl PGE2; 15-Methylprostaglandin E2; Arbaprostil; 11α,15α-Dihydroxy-15-methyl-9-oxoprosta-5,13-dien-1-oic acid; U-26,873; 15-Methyl-PGE2; (5Z,13E)-(9S,11R,15S)-11,15-Dihydroxy-15-methyl-9-oxoprosta-5,13-dien-1-oic Acid
EINECS	Contact for details

Quality Control

Our 15(S)-15-Methyl Prostaglandin E2 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets exacting standards for research and pharmaceutical development. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.