Description

15(S)-15-Methyl Prostaglandin E1 is a synthetic analog of the naturally occurring prostaglandin E1 (Alprostadil), featuring a methyl group at the 15-position which enhances its metabolic stability. This modification makes it a valuable compound for pharmaceutical research and development, particularly in studying vascular and smooth muscle physiology. It is primarily utilized by researchers and manufacturers in the life sciences sector for developing novel therapeutic agents and conducting advanced biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of advanced prostaglandin-based drugs.
• Biomedical Research: Used as a reference standard and active agent in studies of vascular tone, platelet aggregation, and inflammation pathways.
• Drug Discovery: Employed in high-throughput screening and the development of new treatments for cardiovascular diseases and erectile dysfunction.
• Cell Culture & Signaling Studies: Applied in vitro to investigate the role of prostaglandin receptors in cellular processes.

Basic Information

Product Name	15(S)-15-Methyl Prostaglandin E1
CAS No.	35700-26-6
Molecular Formula	C21H36O5
Molecular Weight	368.51 g/mol
Synonyms	15(S)-15-Methyl PGE1; 15-Methylprostaglandin E1; 15-Methyl-alprostadil; (5Z,13E)-(9S,11R,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid; 15-Methyl Prostaglandin E1; 15-Me-PGE1; 15(S)-MePGE1; 15-Methyl Prostaglandin E1 (15S)
EINECS	Contact for details

Quality Control

Our 15(S)-15-Methyl Prostaglandin E1 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. The product is light-sensitive and easily oxidized; allow it to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Assay	95.0% - 105.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.