Description

15(S)-15-Methyl Prostaglandin is a synthetic analog of naturally occurring prostaglandins, specifically engineered with a methyl group at the 15-position to enhance its metabolic stability and biological activity. This modification makes it a valuable tool compound and intermediate for advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector, particularly those focused on inflammation, reproductive health, and cardiovascular studies, where precise control over prostaglandin signaling pathways is critical.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of more complex prostaglandin-based therapeutics.
• Biochemical Research: Used as a reference standard and active agent in studies of prostaglandin receptors (EP, FP, etc.) and their downstream signaling mechanisms.
• Cell Culture & In Vitro Studies: Employed to investigate cellular processes such as smooth muscle contraction, inflammation mediation, and regulation of intraocular pressure.
• Drug Discovery Programs: Serves as a core structure for the development of novel anti-inflammatory, anti-glaucoma, and cytoprotective agents.
• Metabolic Pathway Analysis: A tool for studying the biosynthesis and degradation pathways of eicosanoids.

Basic Information

Product Name	15(S)-15-Methyl Prostaglandin
CAS No.	35700-21-1
Molecular Formula	C21H36O5
Molecular Weight	368.51 g/mol
Synonyms	15(S)-15-Methyl-PGF2α; 15-Methylprostaglandin F2α; 15-Methyl PGF2α; (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxy-15-methylprosta-5,13-dien-1-oic acid; 15-Methyl-dinoprost; 15-Me-PGF2α; U-36,384; Prostaglandin 15(S)-15-methyl F2α
EINECS	Contact for details

Quality Control

Our 15(S)-15-Methyl Prostaglandin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing specific results for purity, related substances, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.