Description

3,5-Bis(Trifluoromethyl)Fluorobenzene is a specialized fluorinated aromatic building block of significant importance in advanced chemical synthesis. Its value lies in the unique reactivity and electronic properties imparted by the trifluoromethyl and fluorine substituents, which are critical for modulating the characteristics of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries, where it serves as a key intermediate for creating compounds with enhanced stability, bioavailability, and performance.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system and anti-inflammatory agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the fluorine atoms contribute to improved metabolic stability and efficacy.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in catalysis, enabling more efficient and selective chemical transformations in fine chemical manufacturing.
• Materials Science: Incorporated into the synthesis of specialty polymers, liquid crystals, and electronic materials to impart desirable properties like chemical resistance and thermal stability.
• Organic Synthesis Reagent: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution reactions to introduce fluorinated aryl groups.

Basic Information

Product Name	3,5-Bis(Trifluoromethyl)Fluorobenzene
CAS No.	35564-19-3
Molecular Formula	C8H3F7
Molecular Weight	232.10 g/mol
Synonyms	1-Fluoro-3,5-bis(trifluoromethyl)benzene; 3,5-Bis(trifluoromethyl)phenyl fluoride; α,α,α,α',α',α'-Hexafluoro-3-fluoromesitylene; 3-Fluoro-α,α,α,α',α',α'-hexafluoromesitylene; Benzene, 1-fluoro-3,5-bis(trifluoromethyl)-; 3,5-Di(trifluoromethyl)fluorobenzene
EINECS	Contact for details

Quality Control

Our 3,5-Bis(Trifluoromethyl)Fluorobenzene is produced under stringent quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency that meets the exacting standards of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials such as strong bases and reducing agents. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Density (at 20°C)	~1.6 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.