Description

(13R,14R)-14,19-Dihydro-12,13-Dihydroxy-20-Norcrotalanan-11,15-Dione 4-Oxide is a complex pyrrolizidine alkaloid derivative with a highly functionalized structure. This compound is of significant interest in advanced organic synthesis and pharmaceutical research due to its intricate stereochemistry and potential as a key intermediate or pharmacophore. It is primarily sought by research institutions and chemical manufacturers engaged in the development of novel bioactive molecules, particularly within medicinal chemistry and alkaloid synthesis programs.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex natural product analogs and potential drug candidates.
• Medicinal Chemistry Research: Used as a reference standard or a starting material for structure-activity relationship (SAR) studies targeting specific biological pathways.
• Alkaloid Chemistry: A valuable compound for academic and industrial research focused on the synthesis, modification, and biological evaluation of pyrrolizidine alkaloids.
• Biochemical Tool: May be utilized in biochemical assays to study enzyme interactions or receptor binding mechanisms related to its structural class.
• Advanced Organic Synthesis: Employed in methodological development for constructing challenging stereocenters and heterocyclic systems.

Basic Information

Product Name	(13R,14R)-14,19-Dihydro-12,13-Dihydroxy-20-Norcrotalanan-11,15-Dione 4-Oxide
CAS No.	35337-98-5
Molecular Formula	C₁₆H₂₁NO₆
Molecular Weight	323.34 g/mol
Synonyms	12,13-Dihydroxy-14,19-dihydro-20-norcrotalanan-11,15-dione 4-oxide; (13R,14R)-(-)-12,13-Dihydroxy-14,19-dihydro-20-norcrotalanan-11,15-dione 4-oxide; Heliotridine 3α,7α-diol 11,15-dione 4-oxide; A pyrrolizidine alkaloid N-oxide derivative; Retronecine N-oxide derivative; 20-Norcrotalanan-11,15-dione, 14,19-dihydro-12,13-dihydroxy-, 4-oxide, (13R,14R)-
EINECS	Contact for details

Quality Control

Our production of (13R,14R)-14,19-Dihydro-12,13-Dihydroxy-20-Norcrotalanan-11,15-Dione 4-Oxide adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research applications. All materials are characterized using advanced analytical techniques including NMR, HPLC, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The container should be kept in a well-ventilated area and protected from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.