Description

(-)-Kinamycin C CAS NO 35303-08-3 is a structurally complex, bioactive natural product belonging to the kinamycin class of antibiotics, characterized by its unique diazofluorene core. This compound is of significant interest in advanced pharmaceutical research due to its potent biological activity, particularly as a DNA-cleaving agent and a promising scaffold for anticancer drug discovery. It serves as a critical reference standard and a key intermediate for researchers and developers in the fields of medicinal chemistry, oncology research, and synthetic biology.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for analytical method development, validation, and quality control in drug discovery pipelines.
• Medicinal Chemistry Research: Serves as a core structural template for the design, synthesis, and structure-activity relationship (SAR) studies of novel anticancer agents.
• Biochemical Mechanism Studies: Employed in vitro to investigate its mechanism of action, including DNA intercalation, cleavage, and interactions with specific cellular targets.
• Antibiotic Research: Studied for its inherent antibacterial properties and potential as a lead compound for developing new classes of antibiotics.
• Academic & Institutional Research: A vital tool for universities and research institutes conducting fundamental studies in natural product chemistry and bioorganic chemistry.

Basic Information

Product Name	(-)-Kinamycin C
CAS No.	35303-08-3
Molecular Formula	C24H17NO8
Molecular Weight	447.40 g/mol
Synonyms	Kinamycin C; (-)-Kinamycin C; Kinamycin C, (-)-; 35303-08-3; Antibiotic SL 1957C; SL 1957C; 11-Deoxy-4-demethyl-11-oxokinamycin; 1,4,6,11-Tetrahydro-3,10,12-trihydroxy-8,9-dimethoxy-1-methyl-6,11-dioxonaphtho[2,3-c]carbazole-5a-carboxylic acid γ-lactone
EINECS	Contact for details

Quality Control

Our (-)-Kinamycin C is produced under strict quality management protocols to ensure the highest standards of purity and consistency for research applications. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications and test results to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent degradation due to its light-sensitive and easily oxidized nature. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Yellow to orange-red powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.