Description

2-Methyl-2-Phenylpropylmagnesium Chloride is a versatile organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry. Its primary value lies in its ability to act as a robust nucleophile for the formation of carbon-carbon bonds, enabling the synthesis of complex tertiary alcohols and other valuable intermediates. This compound is particularly essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity building blocks for fine chemical synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing tertiary carbon centers and complex molecular scaffolds in active pharmaceutical ingredients (APIs).
• Agrochemical Manufacturing: Used in the production of advanced herbicides, fungicides, and plant growth regulators requiring specific sterically hindered structures.
• Fine Chemical Production: Serves as a fundamental building block for synthesizing specialty chemicals, flavors, and fragrances.
• Material Science Research: Employed in the development of novel polymers, ligands for catalysis, and organic electronic materials.
• Academic & R&D Laboratories: A staple reagent for methodological development and exploratory synthesis in organic chemistry.
• Nucleophilic Addition Reactions: Specifically used for the addition to carbonyl compounds (ketones, aldehydes, esters) and epoxides.

Basic Information

Product Name	2-Methyl-2-Phenylpropylmagnesium Chloride
CAS No.	35293-35-7
Molecular Formula	C10H13ClMg
Molecular Weight	192.96 g/mol
Synonyms	(2-Methyl-2-phenylpropyl)magnesium chloride; Neophylmagnesium chloride; 1-Chloro-2-methyl-2-phenylpropane magnesium; 2-Methyl-2-phenylpropyl Grignard reagent; (2-Methyl-2-phenylpropyl)magnesium chloride solution; Magnesium, chloro(2-methyl-2-phenylpropyl)-; (Neophyl)magnesium chloride
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-Phenylpropylmagnesium Chloride is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Quality is verified through analytical techniques including titration for assay determination and impurity profiling. Certificates of Analysis (COA) detailing concentration, purity, and solvent information are provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. This material is highly volatile and hygroscopic (moisture-sensitive). It must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area, away from heat and ignition sources. For specific temperature recommendations for different solvent formulations, please consult the technical data sheet.

Specification

Item	Specification
Appearance	Colorless to light yellow solution
Identification (IR)	Conforms
Concentration (in specified solvent)	0.5 M - 2.0 M (Typical)
Assay (Titration)	≥ 95.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.