Description

4-Fluoro-1H-Pyrazole is a versatile fluorinated heterocyclic building block of significant importance in modern synthetic chemistry. Its core value lies in the strategic introduction of a fluorine atom into the pyrazole scaffold, enabling the fine-tuning of physicochemical properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Material Science Research: Serves as a building block for creating novel fluorinated polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and fluorinated tags for studying biological systems and drug-target interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	4-Fluoro-1H-Pyrazole
CAS No.	35277-02-2
Molecular Formula	C3H3FN2
Molecular Weight	86.07 g/mol
Synonyms	4-Fluoropyrazole; 1H-Pyrazole, 4-fluoro-; 4-Fluoro-1H-pyrazole; 4-Fluoropyrazole; 4-Fluoro-pyrazole; 4-F-Pyrazole; 4-Fluor-1H-pyrazol; 4-Fluoropyrazol
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1H-Pyrazole is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification parameters. Our quality commitment aligns with the standards required for GMP-grade intermediates and research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.