Description

Epoprostenol is a potent synthetic prostacyclin (PGI2) analog, a critical pharmaceutical active ingredient. Its primary value lies in its powerful vasodilatory and antiplatelet properties, making it essential for managing severe vascular conditions. This high-purity compound is primarily required by pharmaceutical manufacturers and advanced research institutions developing treatments for pulmonary arterial hypertension (PAH) and related cardiovascular disorders.

Application

• Pharmaceutical API: Core active ingredient in injectable formulations for the treatment of pulmonary arterial hypertension (PAH).
• Cardiovascular Research: Vital tool for in vitro and in vivo studies investigating vasodilation, platelet aggregation inhibition, and endothelial function.
• Critical Care Medicine: Used in hospital settings for continuous intravenous infusion in patients with severe, life-threatening PAH.
• Drug Delivery System Development: Research into stable formulations and novel delivery methods due to its inherent instability.
• Reference Standard: Serves as a high-purity analytical standard for quality control and pharmacokinetic studies in pharmaceutical labs.

Basic Information

Product Name	Epoprostenol
CAS No.	35121-78-9
Molecular Formula	C20H32O5
Molecular Weight	352.47 g/mol
Synonyms	Prostacyclin; PGI2; PGX; (5Z,9α,11α,13E,15S)-6,9-Epoxy-11,15-dihydroxyprosta-5,13-dien-1-oic Acid; Flolan® (Brand Name); Veletri® (Brand Name); Cycloprostin; Epoprostenol Sodium
EINECS	Contact for details

Quality Control

Our Epoprostenol is manufactured under strict quality systems suitable for pharmaceutical applications. Each batch undergoes comprehensive analytical testing including HPLC purity assay, related substance profiling, and specific identification to ensure it meets stringent specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with relevant quality standards.

Storage

Preserve in a tightly closed container, protected from light. Due to its strictly light-sensitive and easily oxidized nature, the product must be stored under an inert atmosphere (e.g., nitrogen or argon) at recommended cold chain conditions (typically -20°C or below). The container should be kept in a dry, well-ventilated area away from oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.