Description

n-Acetylleucylargininal is a synthetic peptide aldehyde derivative, specifically designed as a potent and selective inhibitor of certain proteolytic enzymes. This compound matters for researchers and formulators requiring precise control over enzymatic activity in complex biochemical systems. It is primarily needed by the pharmaceutical, biotechnology, and life science research sectors for applications in drug discovery, proteomics, and the study of enzyme mechanisms.

Application

• Protease Inhibition Studies: Used as a key biochemical tool to investigate the function and kinetics of specific serine or cysteine proteases.
• Pharmaceutical Research: Serves as a lead compound or intermediate in the development of novel therapeutic agents targeting pathological enzymatic pathways.
• Biochemical Assay Development: Employed in the design and validation of high-throughput screening assays for enzyme activity.
• Cell Biology & Signal Transduction Research: Utilized to modulate intracellular proteolysis to study processes like apoptosis, protein turnover, and post-translational modification.
• Peptide Chemistry & Medicinal Chemistry: Acts as a specialized building block or reference standard in the synthesis and analysis of peptide-based inhibitors.

Basic Information

Product Name	n-Acetylleucylargininal
CAS No.	35039-75-9
Molecular Formula	C16H30N6O4
Molecular Weight	370.45 g/mol
Synonyms	Ac-Leu-Arg-H; N-Acetyl-Leu-Arg-al; Leupeptin (analog); Acetylleucylargininal; N-Acetyl-L-leucyl-L-argininal; Protease Inhibitor Peptide Aldehyde; L-Leucine, N-acetyl-, L-argininal deriv.
EINECS	Contact for details

Quality Control

Our n-Acetylleucylargininal is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis to ensure stereochemical integrity. Certificates of Analysis (COA) detailing all specifications are provided to guarantee compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. Due to its hygroscopic and moisture-sensitive nature, the container should be allowed to reach room temperature before opening to prevent condensation. For long-term stability, store under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.