Description

3-Hydroxylidocaine is a key pharmaceutical intermediate and metabolite of the local anesthetic lidocaine. This compound matters for its critical role in the synthesis of advanced pharmaceutical agents and in metabolic studies for drug development and safety profiling. It is primarily needed by manufacturers and researchers in the pharmaceutical, biotechnology, and analytical chemistry industries.

Application

• Pharmaceutical intermediate for the synthesis of novel anesthetic and analgesic compounds.
• Reference standard in analytical chemistry for drug metabolism and pharmacokinetic (DMPK) studies.
• Metabolite standard in clinical and forensic toxicology for lidocaine detection and quantification.
• Key building block in research for developing modified local anesthetics with improved profiles.
• Biochemical research tool for studying cytochrome P450 enzyme activity and metabolic pathways.
• Starting material for the preparation of diagnostic reagents and labeled compounds.

Basic Information

Product Name	3-Hydroxylidocaine
CAS No.	34604-55-2
Molecular Formula	C14H22N2O2
Molecular Weight	250.34 g/mol
Synonyms	3-Hydroxylidocaine; 2-(Diethylamino)-N-(2,6-dimethyl-3-hydroxyphenyl)acetamide; Lidocaine 3-Hydroxy Metabolite; 3'-Hydroxylidocaine; Monoethylglycinexylidide, 3-Hydroxy-; MEGX, 3-Hydroxy-; 34604-55-2
EINECS	Contact for details

Quality Control

Our 3-Hydroxylidocaine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.