Description

2,4-Dimethylphenylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, essential for forming new carbon-carbon bonds in complex organic synthesis. Its value lies in its ability to act as a powerful nucleophile, introducing the 2,4-dimethylphenyl group into target molecules with high precision. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing key molecular frameworks and intermediates.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for creating active pharmaceutical ingredients (APIs), particularly in the synthesis of complex aromatic compounds and heterocycles.
• Agrochemical Production: Used in the manufacture of herbicides, fungicides, and other crop protection agents that require specific dimethylphenyl substituents for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Advanced Material Research: Employed in the creation of organic semiconductors, liquid crystals, and polymers where the 2,4-dimethylphenyl moiety modifies electronic or physical properties.
• Fine Chemical Manufacturing: Integral for producing specialty chemicals, dyes, and fragrances that rely on tailored aromatic structures.
• Cross-Coupling Reactions: A vital reagent in Kumada, Negishi, and other palladium-catalyzed cross-coupling methodologies to form biaryl and other complex systems.

Basic Information

Product Name	2,4-Dimethylphenylmagnesium Bromide
CAS No.	34589-46-3
Molecular Formula	C8H9BrMg
Molecular Weight	209.36 g/mol
Synonyms	2,4-Dimethylphenylmagnesium Bromide Solution; (2,4-Dimethylphenyl)magnesium Bromide; Magnesium, bromo(2,4-dimethylphenyl)-; 2,4-Xylylmagnesium Bromide; Bromo(2,4-dimethylphenyl)magnesium; Grignard Reagent (2,4-Dimethylphenyl); 1-Bromo-2,4-dimethylbenzene magnesium derivative
EINECS	Contact for details

Quality Control

Our 2,4-Dimethylphenylmagnesium Bromide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing concentration, assay, and impurity profile. We adhere to cGMP guidelines where applicable, and our quality systems are designed to meet the exacting standards of the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. This compound is highly volatile, easily oxidized, and reacts violently with water and protic solvents. Keep away from heat, sparks, open flames, and strong oxidizing agents. Use only in a certified fume hood with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Clear, colorless to light brown solution
Concentration (in THF or Diethyl Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (Titration)	≥ 95%
Identification (IR / NMR)	Conforms to structure
Water Content (Karl Fischer)	≤ 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.