Description

o-Ethylbenzenesulphonyl Fluoride is a specialized organofluorine compound and a key sulfonyl fluoride derivative. This chemical serves as a versatile and reactive building block in advanced organic synthesis, particularly valued for its role as a sulfonylation reagent. It is primarily utilized by research institutions and industrial R&D departments focused on pharmaceuticals, agrochemicals, and material science. Its unique structure makes it instrumental in constructing complex molecules and developing novel chemical entities.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the development of herbicides, fungicides, and pesticides where the sulfonyl fluoride moiety is required for biological activity.
• Chemical Biology & Proteomics: Acts as a reactive probe in activity-based protein profiling (ABPP) to study enzyme function and discover new drug targets.
• Polymer & Material Science: Employed as a monomer or cross-linking agent to introduce sulfonate groups into polymers, modifying their properties.
• Organic Synthesis Reagent: Functions as an electrophilic fluorinating and sulfonylating agent in various carbon-fluorine and carbon-sulfur bond-forming reactions.
• Ligand & Catalyst Development: Used to synthesize novel ligands and organocatalysts for asymmetric synthesis and transition metal catalysis.

Basic Information

Item	Details
Product Name	o-Ethylbenzenesulphonyl Fluoride
CAS No.	34586-49-7
Molecular Formula	C8H9FO2S
Molecular Weight	188.22 g/mol
Synonyms	2-Ethylbenzenesulfonyl Fluoride; ortho-Ethylbenzenesulfonyl Fluoride; 1-Ethyl-2-sulfonylfluorobenzene; Benzenesulfonyl fluoride, 2-ethyl-; o-Ethylphenylsulfonyl Fluoride; 2-Ethylphenylsulfonyl Fluoride; Ethylbenzenesulfonyl Fluoride (o-isomer)
EINECS	Contact for details

Quality Control

Our o-Ethylbenzenesulphonyl Fluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.