Description

1,2-Dihydro-1-(α,α,α-Trifluoro-m-Tolyl)-3H-Pyrazolo[3,4-B]Pyridin-3-One is a high-purity fluorinated heterocyclic compound that serves as a critical advanced intermediate in modern organic synthesis. Its value lies in its unique molecular scaffold, which is designed to impart specific physicochemical properties to target molecules, making it essential for research and development in demanding fields. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers focused on developing novel active ingredients and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of new-generation pesticides and herbicides, where the trifluoromethyl and pyrazolopyridine structures can contribute to biological activity.
• Material Science Precursor: Serves as a specialized monomer or precursor for synthesizing advanced functional materials, such as organic semiconductors or liquid crystals.
• Chemical Biology Probe: Utilized in medicinal chemistry and chemical biology as a core structure for creating molecular probes to study enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences industry.

Basic Information

Product Name	1,2-Dihydro-1-(α,α,α-Trifluoro-m-Tolyl)-3H-Pyrazolo[3,4-B]Pyridin-3-One
CAS No.	34580-77-3
Molecular Formula	C14H8F3N3O
Molecular Weight	291.23 g/mol
Synonyms	1-(3-(Trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-3-ol; 1-(α,α,α-Trifluoro-m-tolyl)-1H-pyrazolo[3,4-b]pyridin-3-ol; 3-Hydroxy-1-[3-(trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridine; 1-(3-Trifluoromethylphenyl)-1H-pyrazolo[3,4-b]pyridin-3-one; 34580-77-3; 1H-Pyrazolo[3,4-b]pyridin-3-ol, 1-[3-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our production of 1,2-Dihydro-1-(α,α,α-Trifluoro-m-Tolyl)-3H-Pyrazolo[3,4-B]Pyridin-3-One adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. All materials are characterized and tested against rigorous in-house specifications. A comprehensive Certificate of Analysis (COA), detailing purity, identity, and impurity profiles, is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.