Description

1-[[1-[m-(Trifluoromethyl)Phenyl]-1H-Pyrazolo[3,4-B]Pyridin-3-Yl]Oxy]-2-Propanone is a high-value, heterocyclic organic compound featuring a pyrazolopyridine core functionalized with a trifluoromethylphenyl group and a propanone ether linkage. This compound matters as a sophisticated pharmaceutical intermediate and key building block in medicinal chemistry, enabling the synthesis of novel bioactive molecules. It is primarily needed by R&D laboratories and manufacturers in the pharmaceutical, agrochemical, and advanced material sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or oncology.
• Agrochemical Research: Used as a building block for developing new generation herbicides, fungicides, or insecticides, leveraging the biological activity of the pyrazolopyridine scaffold.
• Material Science: Acts as a monomer or functional additive in the research of specialty polymers and advanced organic electronic materials due to its complex aromatic structure.
• Chemical Biology Probe: Employed in academic and industrial research to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds for client projects.

Basic Information

Product Name	1-[[1-[m-(Trifluoromethyl)Phenyl]-1H-Pyrazolo[3,4-B]Pyridin-3-Yl]Oxy]-2-Propanone
CAS No.	34580-66-0
Molecular Formula	C₁₆H₁₂F₃N₃O₂
Molecular Weight	335.28 g/mol
Synonyms	1-({1-[3-(Trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridin-3-yl}oxy)propan-2-one; 2-Propanone, 1-[[1-[3-(trifluoromethyl)phenyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]oxy]-; 1-[[1-(3-Trifluoromethylphenyl)pyrazolo[3,4-b]pyridin-3-yl]oxy]-2-propanone; 34580-66-0; 1-(1-(3-(Trifluoromethyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-3-yloxy)propan-2-one
EINECS	Contact for details

Quality Control

Our 1-[[1-[m-(Trifluoromethyl)Phenyl]-1H-Pyrazolo[3,4-B]Pyridin-3-Yl]Oxy]-2-Propanone is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in dark conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.