Description

2-Methoxy-6-(Trifluoromethyl)Pyridine is a versatile fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both a methoxy and a trifluoromethyl group, provides valuable electronic and steric properties for modulating the activity of target molecules. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances lipophilicity and metabolic stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers and liquid crystals for electronic applications.
• Chemical Biology Probes: Utilized to create fluorinated analogs of bioactive molecules for metabolic and binding studies.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	2-Methoxy-6-(Trifluoromethyl)Pyridine
CAS No.	34486-18-5
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	6-(Trifluoromethyl)-2-methoxypyridine; 2-Methoxy-6-(trifluoromethyl)pyridine; 2-Methoxy-α,α,α-trifluoro-6-picoline; 2-Methoxy-6-trifluoromethylpyridine; 2-Methoxypyridine, 6-(trifluoromethyl)-; 6-Trifluoromethyl-2-methoxypyridine; 2-Methoxy-6-(trifluoromethyl)pyridine, 97+%
EINECS	Contact for details

Quality Control

Our 2-Methoxy-6-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its properties, keep away from strong acids, strong bases, and oxidizing agents. Handle in accordance with good industrial hygiene and safety practice.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Density	~1.3 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.