Description

Silybin Dihemisuccinate is a chemically modified, water-soluble derivative of the natural flavonolignan Silybin, designed to enhance bioavailability. This compound is of significant commercial interest for its potent hepatoprotective and antioxidant properties, offering improved formulation flexibility over its parent molecule. It is primarily sought by manufacturers in the pharmaceutical and nutraceutical industries for the development of advanced liver support supplements and therapeutic agents.

Application

• Pharmaceutical Intermediates: Key active pharmaceutical ingredient (API) for hepatoprotective and liver detoxification formulations.
• Dietary Supplements & Nutraceuticals: Core component in high-potency liver support, antioxidant, and detoxification capsules, tablets, and liquid formulations.
• Cosmeceuticals: Incorporated into anti-aging and protective skincare products for its antioxidant and anti-inflammatory benefits.
• Research & Development: Standard reference material for pharmacokinetic, bioavailability, and efficacy studies in hepatology and phytochemistry.
• Functional Food & Beverages: Ingredient for health-focused drinks and food products targeting liver health and metabolic wellness.
• Veterinary Pharmaceuticals: Used in supplements for liver health support in companion and production animals.

Basic Information

Product Name	Silybin Dihemisuccinate
CAS No.	34482-56-9
Molecular Formula	C33H38O15
Molecular Weight	674.65 g/mol
Synonyms	Silibinin Dihemisuccinate; Silybinin Dihemisuccinate; Silybin Bis(Hydrogen Succinate); Silymarin Component Derivative; 2,3-Dihydro-3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-6-(3,5,7-trihydroxy-4-oxobenzopyran-2-yl)benzodioxin-8-yl hydrogen succinate; 3,5,7-Trihydroxy-2-[3-(4-hydroxy-3-methoxyphenyl)-2-(hydroxymethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]-4-chromanonone dihydrogen butanedioate
EINECS	Contact for details

Quality Control

Our Silybin Dihemisuccinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets high-grade specifications suitable for pharmaceutical and nutraceutical applications. Certificates of Analysis (COA) documenting full compliance with agreed specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed in a dry environment to prevent degradation and clumping.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.2%
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Total Aerobic Microbial Count	≤ 1000 cfu/g
Total Combined Yeasts/Molds	≤ 100 cfu/g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.