Description

4-Chloro-3-(Trifluoromethyl)Benzaldehyde is a versatile fluorinated aromatic aldehyde building block, identified by CAS NO 34328-46-6. This compound is valued for its unique trifluoromethyl and chloro substituents, which impart significant electronic and steric properties crucial for advanced synthesis. It is primarily sought after by research and development chemists and process engineers in the pharmaceutical and agrochemical sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated liquid crystal compounds and electron-transport materials in organic light-emitting diodes (OLEDs).
• Functional Dye & Pigment Chemistry: Employed in the synthesis of specialized dyes and pigments with enhanced light-fastness and unique chromatic properties.
• Cross-Coupling Reactions: The aldehyde and halogen functionalities make it a suitable substrate for Suzuki, Heck, and other palladium-catalyzed cross-coupling reactions to build complex molecular architectures.
• Organic Synthesis Building Block: Utilized in various condensation, reduction, and nucleophilic addition reactions to introduce the 4-chloro-3-(trifluoromethyl)phenyl moiety into target molecules.

Basic Information

Product Name	4-Chloro-3-(Trifluoromethyl)Benzaldehyde
CAS No.	34328-46-6
Molecular Formula	C8H4ClF3O
Molecular Weight	208.56 g/mol
Synonyms	4-Chloro-3-(trifluoromethyl)benzaldehyde; 3-Trifluoromethyl-4-chlorobenzaldehyde; 4-Chloro-alpha,alpha,α-trifluoro-m-tolualdehyde; 4-Chloro-3-trifluoromethylbenzaldehyde; m-Chloro-alpha,alpha,α-trifluorotoluic aldehyde; 2-Chloro-5-formylbenzotrifluoride; 5-Chloro-2-formylbenzotrifluoride; 4-Chloro-3-(trifluoromethyl)benzenecarboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-(Trifluoromethyl)Benzaldehyde is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.