Description

2,6-Difluoropyrazine is a high-purity, fluorinated heterocyclic building block of significant importance in advanced organic synthesis. Its value lies in its ability to act as a versatile precursor for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers in fine chemical, pharmaceutical R&D, and material science industries seeking to introduce fluorine atoms or pyrazine scaffolds into target structures.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of novel drug candidates with improved metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the difluoropyrazine moiety can enhance biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis and material fabrication.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers, due to its electron-deficient aromatic system.
• Fluorine Chemistry Building Block: A valuable starting material for further functionalization, enabling the introduction of the pyrazine ring into more complex fluorinated architectures.

Basic Information

Product Name	2,6-Difluoropyrazine
CAS No.	33873-09-5
Molecular Formula	C4H2F2N2
Molecular Weight	116.07 g/mol
Synonyms	2,6-Difluoropyrazine; Pyrazine, 2,6-difluoro-; 2,6-Difluoro-1,4-diazine; 2,6-Difluoropyrazine (DFP); 2,6-Difluoro-1,4-diazabenzene; 2,6-Difluoropyrazine, 98+%; 33873-09-5
EINECS	Contact for details

Quality Control

Our 2,6-Difluoropyrazine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.