Description

Prostaglandins F2Alpha Methyl Ester is a chemically modified, stabilized analog of the naturally occurring prostaglandin F2α, designed for enhanced handling and research utility. This compound is a critical intermediate and reference standard in the development of pharmaceutical agents targeting reproductive health, ocular pressure, and inflammatory pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors who require high-purity bioactive molecules for drug discovery and process development.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the production of prostaglandin-based therapeutics.
• Biochemical Research: Used as a reference standard and active agent in studies of smooth muscle contraction, fertility regulation, and luteolysis.
• Ophthalmic Drug Development: Serves as a model compound for researching analogs used in glaucoma treatment.
• Veterinary Medicine: Employed in the development of agents for estrus synchronization and parturition induction in livestock.
• Cell Signaling Studies: A tool compound for investigating FP receptor activation and downstream cellular pathways.
• Process Chemistry & Scale-up: Used in method development and optimization for the commercial synthesis of complex prostaglandin molecules.

Basic Information

Product Name	Prostaglandins F2Alpha Methyl Ester
CAS No.	33854-16-9
Molecular Formula	C₂₁H₃₄O₅
Molecular Weight	366.49 g/mol
Synonyms	PGF2α Methyl Ester; Dinoprost Methyl Ester; (5Z,9α,11α,13E,15S)-9,11,15-Trihydroxyprosta-5,13-dien-1-oic Acid Methyl Ester; Prosta-5,13-dien-1-oic Acid, 9,11,15-trihydroxy-, Methyl Ester, (5Z,9α,11α,13E,15S)-; Methyl (5Z,9α,11α,13E,15S)-9,11,15-trihydroxyprosta-5,13-dien-1-oate; PGF2α-Me; Prostaglandin F2α Methyl Ester
EINECS	Contact for details

Quality Control

Our Prostaglandins F2Alpha Methyl Ester is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and specific tests for related substances and residual solvents. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with research and cGMP-grade material expectations.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.