Description

4-Methyl-1-Piperazinesulfonyl Chloride Hydrochloride is a key sulfonyl chloride derivative used as a versatile building block in advanced organic synthesis. This compound matters for its role in introducing the 4-methylpiperazine-1-sulfonyl moiety, a functional group of significant interest in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for creating sulfonamide-based compounds with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, especially those containing sulfonamide pharmacophores.
• Medicinal Chemistry Research: Used as a versatile reagent for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Sulfonamide Library Synthesis: Enables the efficient preparation of diverse compound libraries for high-throughput screening in biological assays.
• Chemical Biology Probes: Employed in the development of chemical probes to study enzyme function and biological pathways involving sulfonation.
• Agrochemical Development: Potential use as an intermediate in the research and synthesis of new agrochemicals, such as herbicides or fungicides.
• Material Science: Can be utilized in the synthesis of specialized polymers or functional materials requiring sulfonamide linkages.

Basic Information

Product Name	4-Methyl-1-Piperazinesulfonyl Chloride Hydrochloride
CAS No.	33581-96-3
Molecular Formula	C5H12ClN2O2S • HCl
Molecular Weight	247.15 g/mol
Synonyms	1-Piperazinesulfonyl chloride, 4-methyl-, hydrochloride; 4-Methylpiperazine-1-sulfonyl chloride hydrochloride; N-(4-Methylpiperazinyl)sulfonyl chloride hydrochloride; 4-Methyl-1-piperazinesulfonyl chloride HCl; 4-Methylpiperazine sulfonyl chloride hydrochloride; 1-(Chlorosulfonyl)-4-methylpiperazine hydrochloride; 4-Methylpiperazinylsulfonyl chloride hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Methyl-1-Piperazinesulfonyl Chloride Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.